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NMR Spectroscopy in Pharmaceutical Analysis

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The book deals with quantitative NMR spectroscopy by demonstrating the possibilities of the technique and by training the people who have not yet used NMR spectroscopy for assessment of drug, natural products, plant extracts, agrochemicals or food. This book is divided into three parts: part I gives the fundamental of solution and solid-state NMR spectroscopy and its quantitative application as well as the basic of hyphenated techniques. In part II, principal application fields are presented and modi operandi discussed: drug evaluation, polymer characterization, natural compound assessment in mixtures, investigation of drug formulations, metabolic profiling, DOSY (diffusion-ordered spectroscopy) for faked drugs and quality control of agrochemicals. In part III, special applications from various fields are described, e.g. vaccine evaluation, metabolic studies using F and P NMR, 2D techniques for glycosaminoglycan analysis, assessment of the inhibitory potency of antibiotics by glycosaminoglycan analysis, assessment of the inhibitory potency of antibiotics by MRI or hypernation of LC-UV-NMR-MS and its application in industries. This increasing significance of qNMR is currently emphasized by the quality evaluation of heparine contamined with anaphylactoid oversulfated chrondroitin sulfate.

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Detail Information

Series Title

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Call Number

615.1-1 Hol N

Publisher

Amsterdam : Elsevier., 2008

Collation

Ed.1-Cet.1.xxi, 501 hal. Ilus. ; 24,5 cm Index. Hl

Language

Indonesia

ISBN/ISSN

978-0-444-53173-5

Classification

615.1-1 Hol N

Content Type

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Media Type

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Carrier Type

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Edition

NULL

Subject(s)

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