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Antisense Drug Technology: Principles, Strategies, and Applications
Antisense Drug Technology: Principles, Strategies, and applications, second edition reflects the logarithmic progress made in the past four years of oligonucleotide based therapies, and in particular, antisense therapeutics and research. And evaluates the technology as a whole and offers new directions and avenues of research and development. This book divided 5 part. Part 1 is introduction. Part 2 is the basics of oligonucleotide based therapeutics. Part 3A is hybridization based drugs: basic properties 2'-0-methoxyethyl oligonucleotides. Part 3B is hybridization based drugs: basic properties duplex RNA drugs. Part 4 is other chemical classes of drugs. Part 5 is therapeutic applications.
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