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Medicinal Chemistry of Bioactive Natural Products

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Medicinal chemistry of Bioactive Natural Product provides a much needed survey of bioactive natural products and their applications in medicinal chemistry. This comprehensive reference features articles by some of the world's leading scientists in the field on discovery, structure elucidation, and elegant synthetic strategies developed for natural products with an emphasisi on the structure relationship of bioactive natural products. This book has 10 section. Section 1 discuss the chemistry and biology of epothilones-lead structures for the discovery of improved microtubule inhibitors. Section 2 discuss the chemistry and biology of vancomycin and other glycopeptides antibiotic derivatives. Section 3 discuss structure modifications and their influences on antitumor and other related activites of taxol and its analogs. Section 4 discuss the overview of studies on huperzine a: a natural drug for the treatment of alzheimer's disease. Section 5 discuss qinghaosu (artemisinin) a fantastic antimalarial drig from a traditional Chinese medicine. Section 6 discuss progress of studies on the natural cembranoids from the soft coral species of sarcophyton genus. Section 7 discuss medicinal chemistry of ginkgolides from ginkgo biloba. Section 8 discuss recent progress in calophyllum coumarins as potent anti-HIV agents. Section 9 discuss recent progress and prospects on plant-derived anti-HIV and analogs. Section 10 discuss recent progress on the chemical synthesisi of annonaceous acetogenins and their structurally modified mimics.

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Series Title

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Call Number

615.3-1 Lia M

Publisher

New Jersey : JHON WILEY & SONS., 2006

Collation

ed.1-cet.1. xi, 460 hal. Ilus. ; 23,5 cm Index. In

Language

Indonesia

ISBN/ISSN

978-0-471-66007-1

Classification

615.3-1 Lia M

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