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Marks' Basic Medical Biochemistry: a Clinical Approach
CONTENTS
Section one. Fuel metabolism
1. metabolic fuels and dietary components/3
2. the fed or abrsorptive state/22
3. fasting/30
Section two. Chemical and biologic foundations of biochemistry
4. water, acids, bases, and buffers/41
5. structures of the major compounds of the body/54
6. amino acids in proteins/72
7. structure-function relationships in proteins/92
8. enzymes as catalysts/115
9. regulation of enzymes/138
10. relationship between cell biology and biochemistry/157
11. cell signaling by chemical messengers/184
Section three. Gene expression and the synthesis of proteins
12. structure of the nucleic acids/207
13. synthesis of DNA/222
14. transcription: synthesis of RNA/237
15. translation: synthesis of proteins/258
16. regulation of gene expression/274
17. use of recombinant DNA techniques in medicine/297
18. the molecular biology of cancer/317
Section four. Fuel oxidation and the generation of ATP
19. cellular bioenergetics: ATP and O2/341
20. tricarboxylic acid cycle/360
21. oxidative phosphorylation and mitochondrial function/380
22. generation of ATP from glucose: glycolysis/399
23. oxidation of fatty acids and ketone bodies/418
24. oxygen toxicity and free radical injury/439
25. metabolism of ethanol/458
Scetion five. Carbohydarte metabolism
26. basic concepts in regulation of fuel metabolism by insulin, glucagon, and other hormones/477
27. digestion, absorption, and transport of carbohydrates/493
28. formation and degradation of glycogen/511
29. pathways of sugar metbaolism: pentose phospate pathway, fructose, and galactose metabolism/527
30. synthesis og glycosides, lactose, glycoproteins, and glycolipids/542
31. gluconeogenesis and maintenance of blood glucose levels/556
Section six. Lipid metabolism
32. digestion and transport of dietary lipids/583
33. synthesis of faty acids, triacylglycerols, and the major membrane lipids/594
34. cholesterol absorption, synthesis, metabolism, and fate/619
35. metabolism of the eicosanoids/654
36. integration of carbohydarte and lipid metabolism/668
Section seven. Nitrogen metabolism
37. protein digestion and amino acid absorption/687
38. fate of amino acid nitrogen: urea cycle/697
39. synthesis and degradation of amino acids/712
40. tetrahydrofolate, vitamin B12, and S-adenosylmethionine/732
41. purine and pyrimidine metabolism/747
42. intertissue realtionships in the metabolism of amino acids/762
Section eight. Tissue metabolism
43. actions of hormones that regulate fuel metabolism/783
44. the biochemistry of the erythrocyte and other blood cells/805
45. blood plasma proteins, coagulation, and fibrinolysis/827
46. liver metabolism/842
47. metabolism of muscle at rest and during exercise/862
48. metabolism of the nervous system/881
49. the extracellular matrix and connective tissue/905
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