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Effect of Subgingival Application of Hyaluronic Acid Gel as an Adjunct Therapy After Scaling Root Planing in Chronic Periodontitis Patient : A Rapid Review
The most important treatments of periodontal disease is scaling root planing (SRP)
but that is not always efficient to eradicating all periodontal pathogens, local
subgingival application of chemotheurapeutic agents may used as an adjunct for
optimal result. Hyaluronic acid has demonstrated its ability as an inflammatory
treatment. The potential effect of local subgingival application of HA adjunctive to
scaling and root planing were evaluated in this study. This research was conducted
using a rapid review method through the PICO framework based on Preferred
Reporting Items for Systematic Review and Meta-Analysis (PRISMA). A total of 10
articles with an RCT research design were obtained based on the inclusion criteria
and then analyzed qualitatively. An experimental study on 10 articles over a period of
3 to 6 months showed that additional hyaluronic acid treatment was able to produce
better clinical or microbiological parameters in chronic periodontitis patients.
Hyaluronic acid has results in improving PPD, CAL, BOP, and also reduce the
bacterial periodontopathogens such as Fusobacterium nucleatum, Tannerella
forsythia, Aggregatibacter actinomycetemcomitans and Campylobacter rectus so that
HA has the potential to be an alternative as an additional treatment after SRP for
chronic periodontitis patients.
Keywords : hyaluronic acid, adjunct therapy, chronic periodontitis
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